Topiramate Tablets

Description

“Topiramate Tablets 100 mg”–  Topiramate tablets may result in decreased sweating and increased body temperature (fever). People, mainly children, should be watched this signs of decreased sweating and fever, especially in the summer season or hot temperatures. Some people need to be hospitalized because of this condition. If a high fever, a fever that does not go away, or decreased sweating develops, call your healthcare professional or doctor right away.

Topiramate tablets can raise the level of acid in your blood (metabolic acidosis). If left untreated, metabolic acidosis can cause brittle or soft bones (osteoporosis, osteomalacia, osteopenia), and kidney stones, can slow the rate of growth in children, and may harm your baby if you are pregnant. Metabolic acidosis can occur with or without any symptoms.

Medicinal Benefits

TOPIRAMATE is an antiepileptic medicine that is used to serve epilepsy in mono or adjunctive therapy and migraine problems. In Monotherapy epilepsy, It is suggested for patients above 2 years of age with partial-onset or primary generalized tonic-clonic seizures. In Adjunctive therapy epilepsy, topiramate is suggested in patients of 2 to 16 years of age with partial-onset seizures or primary generalized tonic-clonic seizures while in patients more than 2 years of age, This medicine is suggested in patients with seizures associated with Lennox-Gastaut syndrome (LGS). In migraine, this tablet is suggested for prophylaxis of migraine. It works by blocking the voltage-dependent sodium and calcium channels and increasing the inhibitory actions of GABA. In epilepsy, Topiramate controls the uncontrolled activity of nerves in the brain and thus prevents or controls seizures. While in migraine, topiramate tranquilizes the engaged nerve cells in the brain that are responsible for happening migraine.

What is the dosage for topiramate?

• Most popularly, topiramate suddenly-release tablets and drizzle are started in low doses, 25 or 50 mg per day, and then increased at a very slow rate 25 to 50 mg per week otherwise an effective daily dose is reached for treatment of seizures.
  • For children 10 years or older and adults, the dose may be increased by 100 mg in weeks 5 and 6 when topiramate is used alone.
  • This slow slow way of treatment reduces side effects. The endorsed final adult dose of 200-400 mg is regulated as two divided doses daily.
• The starting dose for the children is up to 25 mg (1 to 3 mg/kg/day), taken nightly for the first week.
  • The dose is then increased at 1 or 2-week intervals by 1 to 3 mg/kg/day concluded in two divided doses.
  • The prescribed dose is 5 to 9 mg/kg every day and it will be divided into two doses.
• Migraine is treated 25 mg each night for the first week then increased by 25 mg weekly up to a maximum dose of 100 mg operated in two divided doses.
• Patients should maintain a sufficient fluid intake to minimize the problem of kidney stones.
• The suggested dose for extended-release capsules is 200-400 mg once daily.

Side effects

• Tingling of the arms and legs
• Not feeling hungry
• Nausea
• Change in taste
• Diarrhea
• Weight loss
• Nervousness
• Upper respiratory tract infection

Precautions

• Topiramate may create vision problems that can create permanent loss of vision. Call your doctor right away if you have any eye pain, redness, or any changes in your vision.
• Because of having Topiramate, we can suffer from decreased sweating and increased body temperature. Children and people who are unprotected from hot weather may be more likely to have this side effect.
• After taking topiramate some people thought about suicide. If you feel a sudden change in your mood or if you thought about suicide then immediately ask your doctor.
• Topiramate can reduce bone mineral density, which may increase the problem or fear of developing osteoporosis when this medicine is used by children over long periods.