Metformin 500 mg + Sitagliptin 50 mg Tablets


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Metformin & Sitagliptin are tablets for diabetes that help in blood sugar regulation are metformin and sitagliptin tablets.

Metformin functions by reducing the liver’s production of glucose (sugar) and the intestines’ absorption of it. Sitagliptin functions by controlling the amount of post-meal insulin your body produces.

In people with type 2 diabetes mellitus, metformin and sitagliptin is a combination medication used in conjunction with diet and exercise to enhance blood sugar management. Treatment for type 1 diabetes does not involve metformin or sitagliptin.

How To Use Metformin & Sitagliptin Tablets

  • Before beginning the use of sitagliptin/metformin, as well as each time you receive a refill, read the Medication Guide and, if applicable, the Patient Information Leaflet that was provided by your pharmacist. See your physician or pharmacist if you have any queries.
  • As prescribed by your physician, take this medication orally once a day with a meal, ideally in the evening. Completely swallow the tablets. Never chew or crush the tablets. By doing this, the medication may be released all at once, raising the possibility of adverse consequences. When using this drug, unless your doctor instructs you otherwise, stay hydrated.
  • The dosage is determined by your health status, how you respond to treatment, and any additional medications you may be taking. Make sure your pharmacist and doctor are aware of everything you use, including over-the-counter, prescription, and herbal products. To minimize the possibility of adverse reactions (such as stomach distress), your physician might advise you to begin taking this drug at a lower dosage and progressively raise it. Carefully adhere to your doctor’s directions.
  • To get the most out of this drug, take it daily. Take it at the same time every day to aid in memory. Pay close attention to the food diet, exercise regimen, and pharmaceutical treatment plan that your doctor has prescribed.

Benefits Of Metformin & Sitagliptin Tablets

Tablets containing sitagliptin and metformin have several advantages for the treatment of type 2 diabetes. Here are a few main benefits:

Blood sugar control: By lowering the quantity of sugar the liver produces and enhancing insulin sensitivity, metformin aids lower blood glucose levels. Sitagliptin helps regulate blood sugar levels by increasing the amount of insulin produced in response to meals.

Weight control: Metformin is helpful for people who need to control their weight in addition to their diabetes because it is linked to a slight reduction in body weight.

Cardiovascular health: Research indicates that metformin may improve the cardiovascular system by lowering the risk of heart attacks and strokes, among other things.

Combination therapy: Compared to taking either drug alone, taking metformin and sitagliptin together can have synergistic effects that improve blood sugar control.

Safety profile: After much research, both sitagliptin and metformin are widely regarded as safe when used as directed. Like any medicine, they could have adverse consequences, though, so you should talk to a doctor about any possible side effects.

Side Effects Of Metformin & Sitagliptin Tablets

  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea
  • Decreased appetite
  • Abdominal bloating

Precautions Of Metformin & Sitagliptin Tablets

  • This combination medication was prescribed to you because it can better regulate blood sugar than metformin by alone.
  • Reduce the likelihood of experiencing stomach distress by taking it with food.
  • Take it in combination with a balanced diet and frequent exercise to reduce blood sugar levels.
  • The likelihood of weight gain and hypoglycemia is lower than with other diabetes medications. 
  • While you are taking this medication, keep a regular check on your blood sugar levels. 
  • If you are scheduled for general anaesthetic surgery, let your doctor know about your diabetes management.
  • Sitagliptin and metformin Tablets may result in the rare but deadly condition known as lactic acidosis, which is characterized by rapid or heavy breathing, persistent nausea, vomiting, and stomach pain.